|Arthur Fuk-Tat MAK
Professor and Programme Director & Division Head of Biomedical Engineering
BSc (UIUC), PhD (Northwestern), FHKAAST, FHKIE, SrMIEEE
Resume of Career
Arthur Mak obtained his B.Sc. in Engineering Mechanics with highest honor from University of Illinois at Urbana-Champaign in 1976 and earned his Ph.D. in Biomechanics at Northwestern University in 1980. After spending 3 years of postdoctoral fellowship in Tissues Mechanics under Professor Van Mow at Rensselaer Polytechnic Institute in New York, Arthur took up an Assistant Professorship in Bioengineering and Orthopedic Research at University of Pennsylvania. Arthur joined the Jockey Club Rehabilitation Engineering Center at Hong Kong Polytechnic University in 1988 and became Chair Professor of Rehabilitation Engineering in 1997 and in the same year was appointed as the Head of the Center. In 2005-2009, Arthur served as the Founding Head of the Department of Health Technology and Informatics. Arthur was PolyU’s Associate Vice President (Academic Development) in 2006-2010 and Founding Dean of Students in 2008-2011. In 2011, Arthur joined CUHK as Professor in Biomedical Engineering, both in the Departments of Electronic Engineering and Mechanical & Automation Engineering. Arthur is currently serving as the Director of the Biomedical Engineering Programme and Head of the Graduate Division of Biomedical Engineering at CUHK.
Prof. Mak is serving in the editorial boards of a number of international journals on biomedical engineering and rehabilitation engineering. He is a member of the Asia Pacific Working Group of the International Federation for Medical and Biological Engineering, and a member of the World Council on Biomechanics. He was President of the World Association for Chinese Biomedical Engineers in 2009-2011, and was on the Executive Board of the International Society for Prosthetics and Orthotics in 2007-10. Prof. Mak has held visiting/adjunct faculty positions at Sichuan University, University of Pittsburgh, and Eindhoven University of Technology.
Current Research Interests
Biomaterials & biomechanics in tissue engineering; Modeling of biological tissue damage & regeneration; Musculoskeletal biomechanics; Pressure ulcers; Rehabilitation engineering
Highlights of Recent Achievements
- Arthur has developed a model to simulate the damage accumulation and the subsequent repair of muscles around bony prominences due to repeated epidermal loadings. The theory includes deformational and ischemic damages during loading as well as reperfusion injury upon unloading before healing finally kicks in.
- Arthur and his team have developed a method to coat bioactive molecules deep and uniformly into polymeric biodegradable scaffolds using a porogen transfer approach.
- Arthur and his collaborators have developed a microfluidic method to study the interaction of mesenchymal stem cells with a concentration gradient of bioactive ligands to define efficiently the threshold ligand concentration for effective cellular interactions.
For the past 33 years, Arthur has developed/taught the following courses/areas:
- Continuum Mechanics
- Surface Mechanics
- Intro to Biomedical Engineering
- Transport Processes in Living Systems
- Rehabilitation Engineering
- BME Ethics, Safety and Practice
- Bionic Human and the Future of Being Human
Arthur received the Exemplary Teaching Award in the Department of Electronic Engineering in 2012.
Honors and Awards
- M.E. Amstutz Award, Illinois Society of Professional Engineers, 1974.
- Bronze Tablet (Graduation with Highest Honor), Univ of Illinois at Urbana-Champaign, 1976.
- Kappa Delta Award, Bioelectrical Repair and Growth Society, 1985.
- President's Award of Overall Achievement, Hong Kong Polytechnic University, 1995-1996.
- Bronze Award, Tissue Ultrasound Palpation System (with Zheng YP), 53rd World Exhibition of Innovation, Research & New Technology, Brussels, Nov. 2004.
- Silver Award, Wearable Vital Sign Sensor (with Zheng YP, Wang CZ, Zhou YJ), 54th World Exhibition of Innovation, Research & New Technology, Brussels, Nov. 2005.
External Service in Recent 3 Years
- International Federation of Medical and Biological Engineering - Member, Asia-Pacific Working Group (1994-Present).
- World Association for Chinese Biomedical Engineers - President (2008-2010) and Chairman, World Congress Organizing Committee (2009).
- World Council on Biomechanics - Council Member (2006-present).
- International Society for Prosthetics and Orthotics - Executive Board, Member (2007-2010).
- National Chiao Tong University, Taiwan - Member, Advisory Committee to President on Biomedical Engineering (2009).
- National Taiwan University, Taiwan - Member, Assessment Committee, Graduate Institute of Biomedical Engineering (2010).
- Hong Kong Institution of Engineers - Biomedical Discipline Advisory Panel, Founding Chairman (2004-2006) and Member (2004-present).
- Hong Kong Society for Rehabilitation - Member, Advisory Committee (2007-present).
- The Hong Kong Abilympics - Co-Chairman, Organizing Committee (2011).
- Innovation and Technology Support Programme, Innovation & Technology Commission, HK - Assessor (2009-2012).
- Hong Kong Council for Accreditation of Academic and Vocational Qualifications -Council Member (2009-Present).
Publications for the Past 3 Years
Xiao ZT, Wu YQ, Mak AFT. Accumulation of Loading and Unloading Reperfusion Injury – Modeling for the Propagation of Deep Tissue Ulcers. Journal of Biomechanics. 47(2014): 1658-1664. 2014.
Bian LM, Mak AFT, Wu C, Cheng CYJ, Gu ZW, Zhang XD, Qin L. A Model for Facilitating Translational Research and Development in China: Call for Establishing a Hong Kong Branch of the Chinese National Engineering Research Centre for Biomaterials. Journal of Orthopaedic Translation. 2(2014): 170-176. August 2014.
Sun S, Wong SW, Mak AFT, Cho M. Impact of Oxidative Stress on Cellular Biomechanics and Rho Signaling in C2C12 Myoblasts. Journal of Biomechanics, 47(2014): 3650-3656. 2014.
Yao YF, Xiao ZT, Wong SW, Hsu YC, Cheng T, Chang CC, Bian LM, Mak AFT. The Effects of Oxidative Stress on the Compressive Damage Thresholds of C2C12 Mouse Myoblasts: Implications for Deep Tissue Injury. Annals of Biomedical Engineering. 43(2): 287-296. 2015.
Wong SW, Sun S, Cho M, Lee KKH, Mak AFT. H2O2 Exposure Affects Myotube Stiffness and Actin Filament Polymerization. Annals of Biomedical Engineering. 43(5):1178-1188. 2015.
Duan XX, Chan KT, Lee KKH, Mak AFT. Oxidative Stress and Plasma Membrane Repair in Single Myoblasts after Femtosecond Laser Photoporation. Annals of Biomedical Engineering. Accepted, May 2015. (DOI: 10.1007/s10439-015-134-4)
- Li J, MAK AFT. Transfer of Uniform Cell Adhesion-Enhancing Agent from Vehicles to Pore Wall Surface of Scaffold. Chinese Patent No. 200610107999.5, Granted in May, 2010.
- Koo TKK, MAK AFT, CHAO EYS. Bone Repositioning Device, Method, & System. Chinese Patent Application Number ZL200610108683.8, Granted in May 2010.