Published Papers
2008
Xu L.S., Max Q.-H. Meng and H.L. Ren, "Applicability
of Homogeneous Human Trunk Phantom in Estimating the Radiation Characteristics
of Body-worn Devices," International Journal of Information
Acquisition. March 2008, 5(1): 65-82.
Xu L.S., Max Q.-H. Meng and K.Q. Wang, "Pulse
Image Recognition Using Fuzzy Neural Network," Expert
Systems With Applications, http://dx.doi.org/10.1016/j.eswa.2008.02.028
Xu L.S., Max Q.-H. Meng, H.L. Ren, Y.W. Chan, "Radiation Characteristics of Ingested Wireless Device at Frequencies from 430 MHz to 3 GHz, "Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2008, pp. 1250-1253.
Xu L.S., Max Q.-H. Meng, R. Liu, K.Q. Wang, "Robust Peak Detection of Pulse Waveform Using Height Ratio," Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2008, pp. 3856-3859.
Xu L.S., Max Q.-H. Meng Y.W. Chan, C. Hu and H.B. Wang, "Influence of Anesthetic and Dead Animal Bodies on Ingested Wireless Device," Proceedings of IEEE/ASME International Conference on Advanced Intelligent Mechatronics, July 2-5, 2008, Xi’an China, pp. 176-180.
Xu L.S., Max Q.-H. Meng, C. Shi, K.Q. Wang, N.M. Li, "Quantitative Analyses of Pulse Images in Traditional Chinese Medicine," Medical Acupuncture. September 1, 2008, 20(3): 175-189. http://www.liebertonline.com/doi/abs/10.1089/acu.2008.0632
Xu L.S., Max Q.-H. Meng, H.L Ren, and Y.W. Chan, "Radiation Characteristics of Ingestible Wireless Devices in Human Intestine Following Radio Frequency Exposure at 430, 800, 1200 and 2400 MHz, " Accepted by IEEE Transactions on Antennas and Propagation, 2008.
Xu L.S., Max Q.-H. Meng, and Y.W. Chan, "Effects of Dielectric Parameters of Human Body on Radiation Characteristics of Ingestible Wireless Device at Operating Frequency of 430 MHz," To appear in IEEE Transactions on Biomedical Engineering.
Xu L.S., Max Q.-H. Meng, X.H. Qi, K.Q. Wang, "Morphology Variability Analysis of Wrist Pulse Waveform for Assessment of Arteriosclerosis Status," Accepted by Journal of Medical Systems.
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2007
Xu, L.S., and D. Zhang, "Baseline Wander Correction in Pulse Waveforms Using Wavelet-Based Cascaded Adaptive Filter," Computers in Biology and Medicine.Vol 37, No 5, May 2007, pp. 716-731. [pdf] [Matlab code]
Abstract: Pulse diagnosis is a convenient, inexpensive, painless, and non-invasive diagnosis method. Quantifying pulse diagnosis is to acquire and record pulse waveforms by a set of sensor firstly, and then analyze these pulse waveforms. However, respiration and artifact motion during pulse waveform acquisition can introduce baseline wander. It is necessary, therefore, to remove the pulse waveform’s baseline wander in order to perform accurate pulse waveform analysis. This paper presents a wavelet-based cascaded adaptive filter (CAF) to remove the baseline wander of pulse waveform. To evaluate the level of baseline wander, we introduce a criterion: energy ratio (ER) of pulse waveform to its baseline wander. If the ER is more than a given threshold, the baseline wander can be removed only by cubic spline estimation; otherwise it must be filtered by, in sequence, discrete Meyer wavelet filter and the cubic spline estimation. Compared with traditional methods such as cubic spline estimation, morphology filter and Linear-phase FIR least-squares-error digital filter, the experimental results on 50 simulated and 500 real pulse signals demonstrate the power of CAF filter both in removing baseline wander and in preserving the diagnostic information of pulse waveforms. This CAF filter also can be used to remove the baseline wander of other physiological signals, such as ECG and so on.
Xu, L.S., Max Q.-H. Meng and H.L. Ren, "Effect of Subject Size on Electromagnetic Radiation from Source in Human Body Following 2450MHz Radio Frequency Exposure," The proceedings of the 2007 IEEE International Conference on Integration Technology, 20-23 March 2007, pp. 326-329.
Xu, L.S., Max Q.-H. Meng and K.Q. Wang, "Pulse Image Recognition Using Fuzzy Neural Network," The proceedings of the 29th International Conference of the IEEE Engineering in Medicine and Biology Society, 22-26 Aug. 2007 pp. 3148-3151. .
Xu, L.S., Max Q.-H. Meng and H.L. Ren, "Variation of Radiation Effects and Signal Efficiency with Distance between Electromagnetical Source and Trunk Model," The proceedings of the 29th International Conference of the IEEE Engineering in Medicine and Biology Society, 22-26 Aug 2007, pp. 1184-1187.
H.L. Ren, Max Q.-H. Meng, L.S. Xu, "Indoor Patient Position Estimation Using Particle Filtering and Wireless Body Area Networks," The proceedings of the 29th International Conference of the IEEE Engineering in Medicine and Biology Society, 22-26 Aug 2007, pp. 2277-2280.
Max Q.-H. Meng, C. Hu, X.N. Wang, L.S. Xu, T.X. Ma, "Method and System for Tracking and Location of the Micro-device in Human Body," Chinese Patent, Application No. 200710074398.3(Invention Patent)Applied on May.18th 2007 (In Chinese)
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2006
Xu, L.S., D. Zhang, and K.Q. Wang, and L. Wang, "Arrhythmic Pulses Detection Using Lempel-Ziv Complexity Analysis," EURASIP Journal on Applied Signal Processing 2006 (2006), Article ID 18268, 12 pages.[pdf]
Abstract: Computerized pulse
analysis based on traditional Chinese medicine (TCM) is relatively new in the
field of automatic physiological signal analysis and diagnosis. Considerable
researches have been done on the automatic classification of pulse patterns
according to their features of position and shape, but because arrhythmic
pulses are difficult to identify, until now none has been done to automatically
identify pulses by their rhythms. This paper proposes a novel approach to the
detection of arrhythmic pulses by using the Lempel-Ziv complexity analysis.
Four parameters, one lemma, and two rules, which are the results of heuristic
approach, are presented. This approach is applied on 140 clinic pulses for
detecting seven pulse patterns, not only achieving a recognition accuracy of
97.1% as assessed by experts in TCM, but also correctly extracting the
periodical unit of the intermittent pulse.
D. Zhang, K.Q. Wang, and Xu, L.S., "The Approaches to Extracting the Features of Chinese Pulse Image, "Chinese Patent, Pending number: 200610009639.1(In Chinese [pdf])(No Abstract)
Xu L.S., K.Q. Wang, L Wang, N.M. Li, "Pulse Contour Variability before and after Exercise, "Accepted by 19th IEEE International Symposium on Computer-Based Medical Systems (CBMS 2006), to be held on 22-23 June 2006 in Salt Lake City, Utah USA.
Abstract: This paper compares the radial artery pulses of 105 young graduate students. The radial artery pulses after performing progressive ergometer for five minutes are different from those at rest. All the pulses become floating and fast. The contours of pulses have three kinds of variability. The incisures of 39 subjects become especially low; sometimes the incisures are lower than the onset of pulse waveform. The tidal waves and dicrotic waves of 32 subjects become higher. The pulses of 34 subjects become smooth. Their incisures and dicrotic waves become lower. These changes can instruct the exercise and training of the young students and athletes.
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2005
Xu, L.S., D. Zhang, and K.Q. Wang, "Wavelet-based Cascaded Adaptive Filter for Removing Baseline Drift in Pulse Waveforms, "IEEE Trans. BME, Nov. 2005, pp. 1973-1975.[pdf]
Abstract: This paper presents an energy ratio-based method and a wavelet-based cascaded adaptive filter (CAF) for detecting and removing baseline drift from pulse waveforms. Experiments on 50 simulated and five hundred real pulse signals demonstrate that this CAF outperforms traditional filters both in removing baseline drift and in preserving the diagnostic information of pulse waveforms.
Xu, L.S., K.Q. Wang and L. Wang, "Pulse Waveforms Classification Based on Wavelet Network, "27th IEEE EMBS, Shanghai, China, 01-04 Sept. 2005, pp.4596 - 4599.[pdf]
Abstract: This paper proposes a new
algorithm to classify pulse waveforms based on discrete wavelet network. This paper
selects 4-order discrete Daubechies wavelet as the wavelet node of this wavelet
network to classify six pulse patterns distinctive in shape. 600 pulse records
are used to train this wavelet network and 300 pulse records are used to test
the classifier’s performance. The test results show that this approach has 83%
agreement rate with the experienced experts. Compared with traditional
classificationmethods, it needs not the experience in feature extraction.
Wang L., K.Q. Wang, and Xu, L.S., "Lempel-Ziv Decomposition Based Arrhythmic Pulses Recognition, "27th IEEE EMBS, Shanghai, China, 01-04 Sept. 2005, pp. 4606 - 4609.[pdf]
Abstract: The computerization of traditional Chinese pulse diagnosis (TCPD) is relatively new in the field of automatic physiological signal analysis and diagnosis. The classification of pulse patterns according to their positions and shapes have been intensively investigated, but until now no research in identifying pulses by their rhythms has been found. This paper introduces a method to distinguish rhythmic and arrhythmic pulse patterns and further, applies the Lempel-Ziv decomposition to classify arrhythmic pulses. In the experiment on 140 clinic pulses, our approach was able to classify pulses by their rhythms with an accuracy of 90.7%.
Xu, L.S., K.Q. Wang and L. Wang, "Gaussian Kernel Approximate Entropy Algorithm For Analyzing Irrigularity of Time-Series, "Proceedings of IEEE International Conference on Machine Learning and Cybernetics, 2005, pp. 5605-5608.[pdf]
Abstract: Approximate entropy (ApEn) has been widely used to analyze the complexity of time series. However, the inconsistency that ApEn exhibits not only limits its applications but also raises questions about its validity. Addressing this issue, this paper presents a novel Gaussian kernel approximate entropy (GApEn) algorithm. The experimental results demonstrate that GApEn performs better than ApEn in terms of relative consistency, stability and statistical accuracy.
Patent "An Automatic
Three-Position, Multipoint, Pulse Image Detection Device, "Submitted to USA Patent. (No Abstract)
Patent "Pulse Detection in Traditional Chinese Medicine Using Multiple (pressure / photoelectric / ultrasonic) Sensor, "Submitted to USA Patent.(No Abstract)
D. Zhang, K.Q. Wang, and Xu, L.S., "The Chinese Pulse Image Acquisition Device Which Can Automatically Adjust the Contact Pressure, "Chinese Patent, Pending number: 200520036985.X (In Chinese [pdf]) (No Abstract)
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2004
Xu, L.S., K.Q. Wang, and D. Zhang, "Modern Researches on Traditional Chinese Pulse Diagnosis, "European Journal of Oriental Medicine, vol.4, no.6, pp. 46-54, Winter 2004.(No Abstract)[pdf]
Wang, L., K.Q. Wang, and L.S. Xu, "Recognizing wrist pulse waveforms with improved dynamic time warping algorithm, "Proceedings of 3rd IEEE ICMLC, Shanghai, 26-29 Aug 2004, pp. 3644-3649. [pdf]
Abstract: This paper proposes an improved DTW algorithm to recognize pulse waveform. Our approach avoids the pathologic alignment that can be caused by original DTW algorithm and DDTW algorithm. Extensive experiments on 1000 pulse waveforms demonstrate the effect of our approach. Compared with original DTW and DDTW algorithms, our algorithm reduces the FRR and FAR greatly. By calculating the variabilities between the pulse sample and the five pulse templates, our approach has 92.3% agreement rate with experts.
Wang, K.Q., L. Wang, L.S. Xu, D.H. Wang, "SVM Classification for Discriminating Cardiovascular Disease Patients from Non-cardiovascular Disease Controls Using Pulse Waveform Variability Analysis, "17th Australian Computer Society (ACS) Australian Joint Conference on Artificial Intelligence, 2004, pp. 109-119.(No Abstract)
Wang, L., L.S. Xu, and K.Q. Wang, "Wrist Pulse Waveform Variability Analysis, "Proceedings of the WEC2004, China Science and Technology Press, Shanghai, China, November 2 - 6, 2004, vol. B, pp.247-250.(No Abstract)[pdf]
Xu,L.S. et al., “Physiological
Research into the Pulse Waveforms of 105 Young Students, "Proceedings of 7th
national conference of national conference of integrated medicine, Urumchi,
2004. pp. 86-88. (In Chinese)(No Abstract)
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2003
L.S. Xu, K.Q. Wang, D. Zhang, Y.S. Li, Z.J. Wan, J.
Wang, "Objectifying
Researches on Traditional Chinese Pulse Diagnosis," Informatica Medica Slovenica 2003, August,
pp56-63 [pdf]
Abstract:
This paper describes our recent researches on
objectifying of Traditional Chinese Pulse Diagnosis (TCPD) by means of some
modern signal processing methods. In order to demystify TCPD and prove its
efficiency, its significance, theory and features are briefed firstly.
Secondly, a survey of recent developments in the researches of TCPD is
provided. Thirdly, our researches on baseline removal, monitoring of the pulse
and the feature extraction of the pulse are introduced. Furthermore, our pulse
acquisition diagnosis system is presented. Finally, the prosperities and future
works are also pointed out.
K.Q. Wang, L.S. Xu and D. Zhang, "Approximate Entropy Based Pulse Variability Analysis," Proceedings of the IEEE Symposium on Computer-Based Medical Systems, 2003, p 236-241, [pdf]
Abstract: The dynamical analysis of pulse variability gives new insight into researches of cardiovascular system's dynamics. Firstly, long-term pulse variability analysis for the researches on cardiovascular system was proposed. Secondly, approximate entropy was applied to analyze three groups of long-term pulse waveform's variabilities and we found that the pulses' approximate entropies of patients with cardiovascular disease preferred to smaller value and less irregularity. What's more, the pulse variability of the patient with pacemaker newly implanted was also studied. Finally, the pulse variability's clinical value for cardiovascular system was concluded. (7 refs.)
K.Q. Wang, L.S. Xu, "Pulse Baseline Wander Removal Using Wavelet Approximation," Proceedings of the 30th annual meeting of Computers in Cardiology, 2003
Abstract: Pulse waveform is the key to the Traditional Chinese Pulse Diagnosis. However, its baseline wander introduced in the acquisition may result in misdiagnosis. What’s more, recent advancements in the pulse variability analysis require more accuracy of baseline estimation. In this paper, a wavelet based cascaded adaptive filter (CAF) was presented to remove this drift. The CAF works in two stages. The first stage is a discrete Meyer wavelet approximation and the second stage is a cubic Spline estimation. The experimental results on 50 simulated and 200 real pulse signals demonstrate the powerful effect of CAF both in removing the baseline wander and in preserving the diagnostic information of pulse waveform, comparing with some traditional methods, such as cubic Spline estimation, morphology filter and Linear-phase FIR least-squares-error digital filter. In addition, this CAF is easy to be accomplished and needs no prior knowledge on pulse and its baseline drift. (6 refs.)
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2002
Xu L.S., K.Q. Wang;
D. Zhang, C. Shi, "Adaptive baseline
wander removal in the pulse waveform," Proceedings of the IEEE Symposium on
Computer-Based Medical Systems, 2002, p 143-148(EI:1471598,
ISTP: BV67W) [pdf]
Abstract: Pulse waveform plays an important role in pulse diagnosis, which is the key technique in Traditional Chinese Medicine. However, its baseline wander introduced in the acquisition process will result in misdiagnosis. Therefore a wavelet based cascade adaptive filter to remove this wander is presented in this paper. This cascade adaptive filter works in two stages. The first stage is a discrete Meyer wavelet filter and the second stage is the cubic spline estimation. Comparing with some traditional methods, such as cubic spline estimation and Linear-phase FIR least-squares error minimization digital filter, the proposed approach has better performance for removing the baseline wander of pulse waveform.
Xu L.S., K.Q. Wang;
D. Zhang,"Modern
Researches on Pulse Waveform of TCPD," 2002 International
Conference on Communications Circuits and Systems and West Sino Expositions
Proceedings,
pp1073-1078, June 29-July 1, 2002, Chengdu, China.(No Abstract)
Xu L.S., K.Q. Wang;
D. Zhang,"Overview
of Modern Traditional Chinese Pulse Diagnosis," Proceedings of The
Fourth China-Japan-Korea Joint Symposium on Medical Informatics, pp.110-114, Aug.2, 2002, Beijing,
China.(No Abstract)
Wang K.Q., L.S. Xu, D. Zhang, C. Shi, "TCPD based pulse
monitoring and analyzing," Proceedings. 2002
International Conference on Machine Learning and Cybernetics , Volume: 3 ,
4-5 Nov. 2002 , Page(s): 1366 -1370 vol.3 [pdf]
Abstract: This article presents pulse monitoring and analysis
approaches on Traditional Chinese Pulse Diagnosis (TCPD) by means of modern nonlinear
signal processing technology. Pulse monitoring is significant for the research
on cardiovascular and nervous system. But some interference, such as
respiration, motion artifacts can be greatly brought into the long-term pulse
acquisition. Thus, a cascaded adaptive wavelet filter is designed to solve this
issue. Then analysis of long-term pulse waveform in TCPD is illustrated after
being preprocessed. What’s more, the chaos character of healthy Heart Rate
Variability (HRV) is validated.
徐礼胜,王宽全, 李振国, 张大鹏, "中医脉诊信号处理的现代研究," 中国中西医四诊学术会议,厦门2002(No Abstract)
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